There have been calls over several decades from the Institute of Medicine (IOM) and others for expansion of interprofessional education to prepare graduates for interprofessional collaborative practice as a means to drive higher quality and more cost effective care. Over 10 years ago, LCME (medicine), CCNE (nursing), and ACPE (pharmacy) began meeting to learn with one other.

In 2013, after the formation and publication of the Interprofessional Education Collaborative (IPEC), discussions expanded to include other IPEC-related accreditors, (i.e., CODA [dentistry], CEPH [public health] and COCA [osteopathic medicine]). HPAC was officially founded December 2014 to formally address these interprofessional collaborative meetings, and in 2016, outreach to other health profession accreditors expanded membership and collaboration.